Hi, I might be too curious those days: I am looking for a paper that explains the process of tobacco going into the nose and then passes into the bloodstream and brain or a document that explains how the process is working.I am also curious about all the other alkaloids of tobacco.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424107/
Not a 100 percent match, but really enlightening and will partially answer your question. This article covers freebasing of cigarettes. Most of snuffs are freebased, too.
And this, I hope, explains the rest (except other alkaloids):
https://web.archive.org/web/20180327043109/https://www.bernd-mayer.com/nicotine-the-basics
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